PDSNGL®- H is a premium-grade, single-source Polydeoxyribonucleotide (PDRN) ingredient obtained exclusively from highly purified Levant Hollyhock DNA, purified to contain DNA fragments 50–1500 kDa. Widely used in injection therapy for Anti-inflammatory and supportive for skin anti-microbial and cytotoxicity.
Cat No: EG-RM-PH-1-5 L
PRODUCT INFORMATION
I. TECHNICAL SPECIFICATIONS
Structural / Composition Data
Structure / Formula
PDRN Single source from Levant Hollyhock
Molecular Weight
~50 - 1,500 kDa (Mixture of fragments)
PDRN can be categorized into three molecular weight fractions:
Ultra Low
(50–100 kDa)
Low
(100–500 kDa)
Medium
(500–1500 kDa)
Appearance
Liquid
Concentration
15%
Solubility
Soluble in aqueous buffers (e.g., saline, sterile water)
Form(s) Available
Sterile solution
Stability & Shelf Life
Storage
12 months at 2–8 °C, >24 months at –20 °C
Post-Reconstitution
6-12 months at 2–8 °C
Stability Notes
Protect from light
Quality & Compliance
QC Tests
Confirmed
Media
Buffer PBS
Documentation
Available on request
II. PREPARATION / RECONSTITUTION
General Guidance
Reconstitute with 100 mL sterile PBS.
Recommendations
Use within 8–12 hours refrigerated.
III. MECHANISM & BIOLOGICAL FUNCTION
Mechanism of Action
Binds to and activates the Adenosine A2A Receptor (A2AR). Acts as a "building block" and signaling molecule, promoting tissue repair and modulating inflammation. Promotes angiogenesis via VEGF upregulation.
Biological Claims
• Stimulation of hair growth
• Powerful Anti-Inflammatory Action
•Collagen Synthesis & Fibroblast Proliferation
• Stimulation of Angiogenesis (new blood vessel formation)
• Tissue Regeneration & Wound Healing
IV. APPLICATIONS
Intended Uses
Targeted drug delivery systems
V. PACKAGING & PRESENTATION
Sizes
1-5 Liter
PDSNGL® H
FEATURES AND KIENTICS
PDSNGL®-H is The plant’s flower extract and essential oil have demonstrated selective cytotoxic effects against certain cancer cell lines and may help overcome multi-drug resistance by inhibiting P-glycoprotein. It also shows antimicrobial and anti-inflammatory properties
Anti-cancer
Cytotoxicity
Anti- inflammatory
Antioxidant
Anti- microbial
Anti-Aging
Mechanism of Action
1
PDRN binds to adenosine A2A receptors
2
Initiating a cascade that raises intracellular cAMP levels.
3
PDRN provides ready-made deoxyribonucleotides that act as building blocks for DNA repair
What's inside ?
Anti- Cancer
clinically Used
Broad molecular weight spectrum
Effective cellular stimulation
Bioactive
High-purity extraction
Optimal Delivery System
Cream
Injectables
Hydrogel Matrices
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PDSNGL®-H is a purified polydeoxyribonucleotide derived from the Levant Hollyhock plant. It is developed as a plant-based regenerative ingredient for cosmetic and research applications.
What is Levant Hollyhock?
Levant Hollyhock is a bristly flowering plant that produces a vertical flowering stem emerging from a rosette of leaves in winter.
Its large flowers are typically pink but may vary from dark pink to pale pink or even white.
What are the anti-inflammatory benefits of PDSNGL®-H?
Traditional use of the plant extract suggests soothing and calming properties that may help:
Reduce inflammation
Support skin recovery
Calm irritated or sensitive skin
