PDSNGL® A is a high-purity bioactive obtained from carefully processed Aloe Vera leaves. Produced under controlled conditions to preserve biological activity, and it offers consistent composition, and excellent biocompatibility.
Its acts as anti-inflammatory activity, tissue repair stimulant, promoting cell regeneration, angiogenesis, and, making it a powerful ingredient in wound care, and skin rejuvenation.
Cat No: EG-RM-PDA-1-5 L
PRODUCT INFORMATION
I. TECHNICAL SPECIFICATIONS
Structural / Composition Data
Structure / Formula
Polydeoxyribonucleotide; linear polymer of 2'-deoxyribonucleotides
Molecular Weight
~50 - 1,500 kDa (Mixture of fragments)
PDRN can be categorized into three molecular weight fractions:
Ultra Low
(50–100 kDa)
Low
(100–500 kDa)
Medium
(500–1500 kDa)
Appearance
Liquid
Concentration
15%
Solubility
Soluble in aqueous buffers (e.g., saline, sterile water)
• Plant-based cellular regeneration
• Skin barrier repair and protection
• Antioxidant and anti-inflammatory effects
• Collagen and elastin stimulation
IV. APPLICATIONS
Intended Uses
Targeted drug delivery systems
V. PACKAGING & PRESENTATION
Sizes
1-5 Liters
PDSNGL® A
FEATURES AND KIENTICS
PDSNGL® - A is ideal for wound healing products, anti-aging skin care, and supportive hair-scalp preparations, providing a standardized, high-activity Aloe vera extract with reliable performance in regenerative and cosmetic formulations.
Biocompatible and non-immunogenic
Epithelialization, and collagen synthesis
Derived from purified DNA fragments
Stable
Can be combined with peptides, growth factors, or plant extracts
High-purity extraction
Mechanism of Action
1
PDRN binds to adenosine A2A receptors
2
Initiating a cascade that raises intracellular cAMP levels.
3
PDRN provides ready-made deoxyribonucleotides that act as building blocks for DNA repair
What's inside ?
Biotechnologically produced DNA from Aloe Vera plant.
Purified deoxyribonucleotide chains (50–2000 base pairs).
High biocompatibility for safe application
Minimal immunogenicity
Stimulates tissue repair and cellular regeneration
Promotes angiogenesis
Optimal Delivery System
Creams
Injectable
Hydrogel matrices
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What is PDSNGL®-A and how is it derived from Aloe Vera?
PDSNGL®-A an plant-based DNA, offering regenerative and anti-inflammatory benefits similar to traditional PDRN but from a sustainable source.
What are the recommended concentrations or formulations for topical, injectable, or device-based applications?
Topical products (creams, serums, gels): typically 0.5–5% w/w depending on the desired level of activity and product type.
Device-assisted delivery (micro needling, mesotherapy solutions): generally 0.1–1% in sterile saline or hyaluronic acid carriers.
Injectable or implantable medical devices: concentrations should be determined through in-house validation studies and must comply with local regulatory requirements before clinical use.
What are the storage conditions and shelf life for PDSNGL®-A?
Unopened, dry form: Store at 2–8 °C in its original, tightly sealed container, protected from light and moisture. Under these conditions the shelf life is typically 24 months from date of manufacture.
