PDSNGL™ S

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PDSNGL™S is a premium-grade, single-source Polydeoxyribonucleotide (PDRN) ingredient obtained exclusively from highly purified salmonid sperm DNA, purified to contain DNA fragments 50–1500 kDa. Widely used in injection therapy for hair growth and supportive for skin and wound regeneration.

Cat No.: EG-RM-PDS-1-2ml

PRODUCT INFORMATION

 

 I. TECHNICAL SPECIFICATIONS

Structural / Composition Data

Structure / Formula

 Polydeoxyribonucleotide; linear polymer of 2'-deoxyribonucleotides (50-1500 base pairs)

Molecular Weight

 ~50 - 1,500 kDa (Mixture of fragments)

Appearance

 Liquid

Purity

 ≥ 95% 

Solubility

 Soluble in aqueous buffers (e.g., saline, sterile water)

Form(s) Available

 Sterile solution

Stability & Shelf Life

Storage

 12 months at 2–8 °C>24 months at –20 °C

Post-Reconstitution

  6-12 months at 2–8 °C

Stability Notes

 Protect from light

Quality & Compliance

QC Tests

 Pending validation

Intended Use

 As instructions

Documentation

 Available on request

 

 II. PREPARATION / RECONSTITUTION

General Guidance

 Reconstitute with 1.0 mL sterile water to obtain 100 mg/mL.

Recommendations

 Use within 8–12 hours refrigerated.

 

 III. MECHANISM & BIOLOGICAL FUNCTION

Mechanism of Action

 Binds to and activates the Adenosine A2A Receptor (A2AR). Acts as a "building block" and signaling molecule, promoting tissue repair and modulating inflammation. Promotes angiogenesis via VEGF upregulation. 

Biological Claims

  • Tissue Regeneration & Wound Healing

 • Powerful Anti-Inflammatory Action

 • Stimulation of Angiogenesis (new blood vessel formation)

 • Collagen Synthesis & Fibroblast Proliferation

 

 IV. APPLICATIONS

Intended Uses

 Targeted drug delivery systems

 V. PACKAGING & PRESENTATION

 

Sizes

1000 PPM / vials

5000 PPM / vials

10000 PPM / vials

 

 

 

 

PDSNGL™ S

FEATURES AND KIENTICS

PDSNGL™-S is ideal for incorporation into wound healing products, scar management therapies, anti-aging formulations, and hair-follicle revitalization treatments, where high-purity polynucleotides are desired to stimulate angiogenesis, fibroblast activity, collagen production, and antioxidant defenses.

Sterile lyophilized
Suitable for injectables &microneedles
Stable
Bioactive
High-purity standard for safety
Stimulates skin cell repair

What's inside ?

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Purified DNA fragments

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Effective cellular stimulation

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Clinically used

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Supports hair growth

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Promotes skin healing

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High-purity extraction

Optimal Delivery System

Morning Ritual

Cream

Morning Ritual

Injectables

Morning Ritual

Hydrogel matrices

Common Questions

How does PDSNGL™-S act at the cellular level to promote tissue repair or hair growth?

PDSNGL™-S delivers highly purified, low-molecular-weight polydeoxyribonucleotides that are rapidly metabolized into nucleotides and nucleosides by local enzymes. These building blocks support DNA , accelerate cell metabolism, and activate purinergic (A₂A) receptors, which in turn stimulate fibroblast proliferation, collagen and extracellular-matrix production, angiogenesis, and anti-inflammatory signaling. Together these effects create an optimal microenvironment for faster wound closure, improved skin regeneration, and revitalization of hair follicles through enhanced vascular supply and prolonged anagen (growth) phase activity.

What clinical or preclinical data support the use of PDSNGL™-S in regenerative therapies?

The underlying active—single-source salmon-derived PDRN—has been investigated in multiple peer-reviewed preclinical and clinical studies demonstrating accelerated wound healing, enhanced angiogenesis, and increased hair density when applied topically or via injection.
PDSNGL™-S uses the same active principle but with tighter fragment-size control and enhanced purification to deliver consistent, reproducible performance. 

Does PDSNGL™-S meet GMP or ISO quality standards, and is a Certificate of Analysis available?

Yes. PDSNGL™-S is manufactured under GMP-aligned and ISO-certified quality systems with strict controls on raw material sourcing, endotoxin levels, and microbial contamination. Each production batch is tested for identity, purity, and safety, and a detailed Certificate of Analysis (CoA) is supplied with every shipment to verify compliance with these standards.

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