PDSNGL™ B

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PDSNGL™B from probiotics and it’s a Next-Generation, Bioactive DNA derived from safe probiotic strains, designed to deliver the regenerative power of highly purified polynucleotides in a stable, ready-to-use form.

Its balanced composition makes it ideal for advanced skin rejuvenation, wound repair, and hair-growth–support applications, either on its own or in combination with hyaluronic acid, growth factors, or device-based delivery systems.

PDSNGL™-B is supplied with full traceability and a Certificate of Analysis to ensure safety, consistency, and performance.

Cat Number: EG-RM-PDB-1-2ml

PRODUCT INFORMATION

 

 I. TECHNICAL SPECIFICATIONS

Structural / Composition Data

Structure / Formula

Polydeoxyribonucleotide; linear polymer of 2'-deoxyribonucleotides

Molecular Weight

 ~50 - 1,500 kDa (Mixture of fragments)

Appearance

 Liquid

Purity

 ≥ 95% 

Solubility

 Soluble in aqueous buffers (e.g., saline, sterile water)

Form(s) Available

 Sterile solution

Stability & Shelf Life

Storage

 12 months at 2–8 °C>24 months at –20 °C

Post-Reconstitution

  6-12 months at 2–8 °C

Stability Notes

 Protect from light

Quality & Compliance

QC Tests

 Pending validation

Intended Use

 As instructions

Documentation

 Available on request

 

 II. PREPARATION / RECONSTITUTION

General Guidance

 Reconstitute with 1.0 mL sterile water to obtain 100 mg/mL.

Recommendations

 Use within 8–12 hours refrigerated.

 

 III. MECHANISM & BIOLOGICAL FUNCTION

Mechanism of Action

 Binds to and activates the Adenosine A2A Receptor (A2AR). Acts as a "building block" and signaling molecule, promoting tissue repair and modulating inflammation. Promotes angiogenesis via VEGF upregulation. 

Biological Claims

  • Tissue Regeneration & Wound Healing

 • Powerful Anti-Inflammatory Action

 • Stimulation of Angiogenesis (new blood vessel formation)

 • Collagen Synthesis & Fibroblast Proliferation

 

 IV. APPLICATIONS

Intended Uses

 Targeted drug delivery systems

 

 V. PACKAGING & PRESENTATION

 

Sizes

1000 PPM / vials

5000 PPM / vials

10000 PPM / vials

 

 

 

PDSNGL™ B

FEATURES AND KIENTICS

PDSNGL™-B is a highly purified polynucleotide that safely stimulates collagen synthesis, microcirculation and cell renewal, offering versatile delivery and easy integration into advanced skin and scalp regeneration therapies.

Heat and pH stable
High purity, non-immunogenic, and microbiome-safe
Sustainable, bio fermentation-based technology
Compatible with topical, injectable
probiotic DNA with molecular size (100–800 bp)
Derived from safe probiotic strains

What's inside ?

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Bioactive DNA complex derived from safe probiotic strains.

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Next-generation PDRN with regenerative and anti-inflammatory properties

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Supports hair growth by revitalizing follicles and scalp health

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Promotes skin healing & healthier skin

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Enhances wound care

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High purity grade

Optimal Delivery System

Morning Ritual

Creams

Morning Ritual

Injectables

Morning Ritual

Hydrogel matrices

Common Questions

What is PDSNGL™-B and what makes it unique compared to other polynucleotide or PDRN ingredients?

PDSNGL™-B is a highly purified, polynucleotide sourced from a controlled biological origin. Unlike standard PDRN or generic polynucleotide blends, PDSNGL™-B is produced with tight molecular-weight yielding a reproducible, low-immunogenicity ingredient that is optimized for regenerative dermatology and trichology applications.

How does PDSNGL™-B support tissue regeneration, wound healing or hair growth at the cellular level?

PDSNGL™-B provides bioavailable DNA fragments and nucleotides that act as precursors for cell metabolism and activate adenosine A₂ receptors, leading to increased fibroblast proliferation, collagen synthesis, angiogenesis and improved microcirculation. These combined effects accelerate tissue repair, improve extracellular-matrix quality, and stimulate hair-follicle activity for healthier scalp and hair growth.

Are there any known risk factor, sensitivities or regulatory considerations for using PDSNGL™-B?

PDSNGL™-B is designed to be biocompatible and non-immunogenic, and each batch is tested for endotoxins, residual proteins and microbial contamination.
 

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