PDSNGL® O is a premium-grade, single-source Polydeoxyribonucleotide (PDRN) ingredient obtained exclusively from highly purified Allium capa L. DNA, purified to contain DNA fragments 50–1500 kDa. Widely used in injection therapy for hair growth and supportive for skin and wound regeneration.
Cat NO: EG-RM-PDO-1-5 L
PRODUCT INFORMATION
I. TECHNICAL SPECIFICATIONS
Structural / Composition Data
Structure / Formula
PDRN Single source from Allium capa L.
Molecular Weight
~50 - 1,500 kDa (Mixture of fragments)
PDRN can be categorized into three molecular weight fractions:
Ultra Low
(50–100 kDa)
Low
(100–500 kDa)
Medium
(500–1500 kDa)
Appearance
Liquid
Concentration
15%
Solubility
Soluble in aqueous buffers (e.g., saline, sterile water)
Form(s) Available
Sterile solution
Stability & Shelf Life
Storage
12 months at 2–8 °C, >24 months at –20 °C
Post-Reconstitution
6-12 months at 2–8 °C
Stability Notes
Protect from light
Quality & Compliance
QC Tests
Confirmed
Media
Buffer PBS
Documentation
Available on request
II. PREPARATION / RECONSTITUTION
General Guidance
Reconstitute with 100 mL sterile PBS.
Recommendations
Use within 8–12 hours refrigerated.
III. MECHANISM & BIOLOGICAL FUNCTION
Mechanism of Action
Binds to and activates the Adenosine A2A Receptor (A2AR). Acts as a "building block" and signaling molecule, promoting tissue repair and modulating inflammation. Promotes angiogenesis via VEGF upregulation.
Biological Claims
• Stimulation of hair growth
• Powerful Anti-Inflammatory Action
•Collagen Synthesis & Fibroblast Proliferation
• Stimulation of Angiogenesis (new blood vessel formation)
• Tissue Regeneration & Wound Healing
IV. APPLICATIONS
Intended Uses
Targeted drug delivery systems
V. PACKAGING & PRESENTATION
Sizes
1-5 Liter
PDSNGL® O
FEATURES AND KIENTICS
PDSNGL®- O is ideal for incorporation into wound healing products, scar management therapies, anti-aging formulations, and hair-follicle revitalization treatments, where high-purity polynucleotides are desired to stimulate angiogenesis, fibroblast activity, collagen production, and antioxidant defenses.
Sterile
Suitable for injectable µneedles
Stable
Bioactive
Stimulates skin cell repair
High-purity
Mechanism of Action
1
PDRN binds to adenosine A2A receptors
2
Initiating a cascade that raises intracellular cAMP levels.
3
PDRN provides ready-made deoxyribonucleotides that act as building blocks for DNA repair
What's inside ?
Purified DNA fragments
Promotes skin healing
support hair growth
clinically used
high-purity Extraction
Effective cellular stimulation
Optimal Delivery System
Cream
Injectables
Hydrogel Matrices
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PDSNGL® A
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Onion PDRN activates A2A adenosine receptors, which leads to:
Reduction of inflammation
Increased blood circulation
Stimulation of fibroblasts
Enhanced collagen and elastin production
Faster tissue regeneration
What are the main benefits of Onion-Derived PDRN?
Skin benefits
Anti-aging & wrinkle reduction
Collagen stimulation
Skin repair & regeneration
Improved elasticity and hydration
Reduction of redness and irritation
Hair & scalp benefits
Regeneration of hair follicles
Stimulates hair growth
Improves scalp health
Reduces inflammation of the scalp
Is Onion PDRN suitable for cosmetic formulations?
Yes. It is highly suitable for:
Serums
Ampoules
Creams
Scalp treatments
Mesotherapy formulations
