Sodium DNA (DNA-Na) is the sodium salt form of highly purified, depolymerized natural DNA (typically extracted from Oncorhynchus keta).
It appears as a fine, off-white to white, hygroscopic powder. When reconstituted in sterile water or physiological buffer, it forms a clear, viscous solution. In cosmetics, regenerative medicine, and biotechnology, sodium DNA is valued for its polynucleotide content, which can support cell metabolism, tissue repair, and antioxidant defense.
Cat No.: EG-RM-SDNA-1-2ml
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PRODUCT INFORMATION |
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I. TECHNICAL SPECIFICATIONS |
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Structural / Composition Data |
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Structure / Formula |
Sodium salt of deoxyribonucleic acid (DNA) |
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Molecular Weight |
~500–1000 Da (variant dependent) |
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Appearance |
White – Off White Powder |
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Purity |
≥ 95% |
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Solubility |
Soluble in aqueous buffers |
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Form(s) Available |
Lyophilized powder |
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Stability & Shelf Life |
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Storage |
12 months at 2–8 °C, >24 months at –20 °C |
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Post-Reconstitution |
6-12 months at 2–8 °C |
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Stability Notes |
Protect from light |
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Quality & Compliance |
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QC Tests |
Pending validation |
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Intended Use |
As instructions |
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Documentation |
Available on request |
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II. PREPARATION / RECONSTITUTION |
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General Guidance |
Reconstitute with 1.0 mL sterile water to obtain 100 mg/mL. |
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Recommendations |
Use within 8–12 hours refrigerated. |
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III. MECHANISM & BIOLOGICAL FUNCTION |
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Mechanism of Action |
Provides nucleic acid building blocks for cellular processes. Can interact with cellular receptors and participate in various biochemical pathways depending on application. |
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Biological Claims |
- Nucleic acid source for research and manufacturing - Substrate for enzymatic reactions - Template for PCR and molecular biology applications - Raw material for cosmetic and pharmaceutical formulations |
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IV. APPLICATIONS |
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Intended Uses |
Targeted drug delivery systems |
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V. PACKAGING & PRESENTATION |
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Sizes |
100g/ vials |
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Sodium DNA is essentially a purified, depolymerized DNA fragment mixture (polynucleotides of varying lengths) where the phosphate groups are paired with sodium ions. It does not contain proteins, sugars, or lipids — it’s just nucleic acid fragments in salt form.
Sodium DNA – A purified, water-soluble form of DNA salt.
Sourced from high-quality salmon DNA.
Depolymerized Chains – Designed for optimal skin absorption.
Nucleotide-Rich Composition – Supports skin cell structure.
High Purity Grade – Suitable for cosmetic or dermatological use.
bioactive Format – Safe and stable for daily skincare application.
Creams
Injectables
Hydrogel Matrices
Sodium DNA is highly purified from Salmon Salar, depolymerized DNA that has been converted into its sodium salt form. and then processed to create shorter, uniform fragments called polynucleotides.
This makes it more soluble, more stable, and easier to formulate than high-molecular-weight “regular” DNA extracted directly from cells.
Yes. When produced under cosmetic or medical-grade standards, Sodium DNA is considered biocompatible and largely non-immunogenic. Because the polynucleotide fragments are naturally occurring and low in protein or endotoxin contaminants, the body generally recognizes them as nucleic acid building blocks rather than as foreign antigens. This is why Sodium DNA is widely used in topical, injectable, and regenerative formulations without triggering immune reactions.
Once applied or injected, Sodium DNA fragments:
Provide raw materials for cell metabolism, DNA/RNA synthesis, and energy pathways.
Activate cell receptors (e.g., purinergic receptors such as A₂A) and signaling pathways that promote fibroblast proliferation, collagen production, angiogenesis, and anti-inflammatory responses.
Together these effects help support tissue repair, improve skin regeneration, and reduce oxidative stress at the site of application.
Next-Generation Life Science Products for Everyday Health.