PDRN® Complex

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PDRN COMPLEX is an advanced PDRN complex formulation combining DNA fragments obtained from multiple high-purity biological sources 

This biocompatible, non-immunogenic complex supplies the nucleotides needed for DNA repair, and cellular energy recovery while stimulating angiogenesis, fibroblast activity, collagen production, and antioxidant defense.

Through these combined actions, PDRN accelerates wound healing, and revitalizes hair follicles by enhancing blood flow and prolonging the hair growth phase. 

Cat No: EG-RM-PDX-1-5 L
 

PRODUCT INFORMATION

 

 I. TECHNICAL SPECIFICATIONS

Structural / Composition Data

Structure / Formula

 Triple-source polynucleotide complex 

Molecular Weight

~50 - 1,500 kDa (Mixture of fragments)
 PDRN can be categorized into three molecular weight fractions:

Ultra Low

(50–100 kDa)

Low

(100–500 kDa)

Medium

(500–1500 kDa)

Appearance

 Liquid

Concentration

 15% 

Solubility

 Soluble in aqueous buffers

Form(s) Available

 Sterile solution

Stability & Shelf Life

Storage

 12 months at 2–8 °C>24 months at –20 °C

Post-Reconstitution

  6-12 months at 2–8 °C

Stability Notes

 Protect from light

Quality & Compliance

QC Tests

 Confirmed 

Media

 Buffer PBS

Documentation

 Available on request

 

 II. PREPARATION / RECONSTITUTION

General Guidance

 Reconstitute with 100 mL sterile PBS.

Recommendations

 Use within 8–12 hours refrigerated.

 

 III. MECHANISM & BIOLOGICAL FUNCTION

Mechanism of Action

 Multi-pathway activation: A2A receptor binding + integrin signaling + plant-derived antioxidant protection → synergistic tissue regeneration

Biological Claims

• Stimulation of hair growth 

 • Powerful Anti-Inflammatory Action

 •Collagen Synthesis & Fibroblast Proliferation

 • Stimulation of Angiogenesis (new blood vessel formation)

 • Tissue Regeneration & Wound Healing

 

 IV. APPLICATIONS

Intended Uses

 Targeted drug delivery systems

 

 V. PACKAGING & PRESENTATION

 

Sizes

 

1-5 Liter

       
               

 

PDRN® Complex

FEATURES AND KIENTICS

PDRN®- C is a highly purified, biocompatible polynucleotide extract from biological source DNA that supplies essential nucleotides to stimulate tissue repair, collagen production, angiogenesis, and hair follicle reactivation for advanced regenerative care.

Fibroblast Activation and hair growth
Antioxidant Support
Supports anti-aging
wound healing
Anti-inflammatory
Increases skin elasticity & Hydration

Mechanism of Action

1
PDRN binds to adenosine A2A receptors
2
initiating a cascade that raises intracellular cAMP levels.
3
PDRN provides ready-made deoxyribonucleotides that act as building blocks for DNA repair
Mechanism illustrative image

What's inside ?

.

inside_image1

PDRN-rich DNA fragments from biological source for skin regeneration.

inside_image2

Broad molecular weight spectrum – from short-chain oligonucleotides to long DNA strands

inside_image3

Probiotic to balance skin microbiome.

inside_image4

Aloe vera extract to soothe, hydrate, and support healing.

inside_image5

Multi-source synergy for enhanced, long-lasting regenerative activity.

inside_image6

High-purity formulation ensuring safety and effectiveness.

Optimal Delivery System

Morning Ritual

Creams

Morning Ritual

Injectables

Morning Ritual

Hydrogel matrices

Common Questions

What is the chemical and biological composition of PDSNGL®-C?

PDSNGL®-C is a highly purified polynucleotide complex composed mainly of depolymerized DNA fragments (polydeoxyribonucleotides).
These fragments are typically 50–1500 base pairs long and derived from a controlled marine biological source .

How does PDSNGL®-C differ from standard PDRN or other polynucleotide products?

While both PDSNGL® -C and conventional PDRN consist of DNA fragments, PDSNGL®-C is produced with tighter molecular-weight control and enhanced purification. This results in a more uniform fragment profile, higher nucleotide bioavailability and improved stability in solution. 

Can PDSNGL®-C be combined with other active ingredients or delivery systems (e.g., microneedling, PRP, or hyaluronic acid)?

Yes. PDSNGL®-C is biocompatible and chemically stable in aqueous formulations, making it compatible with a wide range of delivery modalities. It can be incorporated into injectables with hyaluronic acid, combined with platelet-rich plasma (PRP), or applied during microneedling and mesotherapy sessions. Such combinations are frequently used to enhance tissue repair, hydration, and hair-follicle revitalization. As with any formulation, compatibility testing and adherence to local regulatory guidelines are recommended before clinical use.

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